Updated at: 11-07-2023 - By: John Lau

You’ve probably asked yourself, “Can I take Aleve with alcohol?”

The truth is, although common, combining this over-the-counter pain reliever with your favorite cocktail could potentially carry significant health risks.

This blog will unravel the complexities of taking Aleve and alcohol together, outlining potential dangers like increased stomach bleeding risk and possible liver damage.

Let’s dive in to discover why it’s crucial to understand the impact of mixing these substances on your body.

Risks of Combining Aleve and Alcohol

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Increased risk of stomach bleeding

Combining Aleve and alcohol can exponentially increase your risk of stomach bleeding, an often dangerous condition. This is especially true if you’re consuming high amounts of alcohol regularly or suffering from alcoholism.

The active ingredient in Aleve, naproxen, already poses a risk for stomach issues like gastritis and ulcers. Alcohol consumption further escalates this situation by intensifying these effects.

Scientists believe that both substances independently irritate the digestive system, so taking them together potentially causes even more harm than either does alone.

This means people misusing naproxen or habitually mixing it with alcohol are at a higher probability of developing serious gastrointestinal complications such as bleeding ulcers – definitely not something anyone would want to experience!

Make sure to follow any guidelines given by your healthcare provider on dose limits and usage frequency to avoid such problems – better safe than sorry!

Potential liver damage

The active ingredient in Aleve, naproxen, is processed by the liver, and alcohol can interfere with this process. When alcohol and naproxen are combined, it puts extra stress on the liver and may lead to inflammation or even long-term damage.

Over time, excessive consumption of alcohol while taking Aleve can increase the risk of developing liver problems such as hepatitis or cirrhosis. It’s important to be aware of these risks and avoid mixing alcohol with medications like Aleve to protect your liver health.

Worsening of side effects

Combining Aleve and alcohol can lead to worsening of side effects. Alcohol can amplify the drowsiness, dizziness, and lightheadedness caused by Aleve, making these symptoms more severe. This can impair your ability to drive or operate machinery safely.

Moreover, both alcohol and Aleve can cause dehydration when consumed in excess, potentially leading to increased fatigue and reduced kidney function.

It is crucial to understand the potential risks associated with mixing Aleve and alcohol in order to make informed decisions about your health and well-being.

When to Seek Medical Assistance

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Severe side effects or reactions

Severe side effects or reactions can occur when combining Aleve with alcohol. This includes an increased risk of stomach bleedingpotential liver damage, and worsening of the medication’s side effects.

Alcohol can amplify the negative effects of Naproxen, the active ingredient in Aleve, leading to serious complications. It is crucial to be aware of any persistent or worsening symptoms and seek medical assistance if needed.

Consulting with a healthcare professional about the risks involved in mixing Aleve and alcohol is also highly recommended to ensure your safety and well-being.

Use Aleve as directed and drink responsibly if necessary to minimize any potential harm that may arise from this combination.

Persistent or worsening symptoms

These symptoms could indicate potential complications arising from the combination of these substances.

Persistent stomach pain, black or bloody stools, vomiting blood, or any other alarming symptoms should not be ignored. It is important to remember that both Aleve and alcohol can have adverse effects on the gastrointestinal system, increasing the risk of stomach bleeding and other digestive issues.


In conclusion, it is not recommended to take Aleve with alcohol due to the increased risk of stomach bleedingpotential liver damage, and worsening of side effects.

To minimize risks, it’s best to avoid alcohol while taking Aleve and consult with a healthcare professional for guidance.

Always follow recommended dosage and guidelines to ensure your safety.