Updated at: 11-08-2023 - By: John Lau

Ever wondered, “Can You Drink On Advil?” It’s not uncommon to consider reaching for a glass of wine or beer while on this commonly used pain reliever.

This blog will guide you through the potential risks and safety measures of mixing ibuprofen and alcohol, providing a comprehensive understanding for your health concerns.

Risks of Mixing Ibuprofen and Alcohol

Can You Drink On Advil (1)

Gastrointestinal bleeding

Gastrointestinal bleeding is a serious risk when mixing ibuprofen and alcohol. The combination of these two substances can irritate the lining of your stomach and intestines, causing them to bleed.

Ibuprofen blocks certain enzymes that protect your digestive tract, leaving it vulnerable to damage by stomach acid. Alcohol heightens this problem by increasing the production of stomach acid, creating a kind of double-whammy effect on your gut.

This can result in nausea, vomiting blood or material that looks like coffee grounds – symptoms indicating potential internal bleeding – which should prompt immediate medical attention. Particularly for older adults or those with existing health conditions, this cocktail could increase the danger manifold.

Kidney damage

Ibuprofen is processed by the kidneys, and alcohol can have a detrimental effect on their functioning. When alcohol is consumed, it causes dehydration and increases the workload on the kidneys.

This can impair their ability to filter out waste products from the blood efficiently.

Furthermore, both ibuprofen and alcohol have been known to cause acute kidney injury in some cases. Ibuprofen may decrease blood flow to the kidneys, reducing their ability to flush out toxins effectively, especially when combined with alcohol consumption.

Decreased alertness

Mixing ibuprofen with alcohol can lead to decreased alertness. Both substances have sedative effects on the body, and when combined, they intensify these effects. This can impair your ability to think clearly, react quickly, and make sound judgments.

It’s important to remember that even small amounts of alcohol can enhance the drowsiness caused by ibuprofen. Therefore, it is recommended to avoid driving or operating machinery while under the influence of this combination.

Be mindful of your body’s response and prioritize your safety when considering whether or not to consume alcohol while taking Advil or any other painkiller containing ibuprofen.

Other side effects of ibuprofen

In addition to the potential risks of mixing ibuprofen and alcohol, there are other side effects of ibuprofen that you should be aware of. While these side effects may not be directly related to consuming alcohol, it’s important to consider them when deciding whether or not to drink while taking Advil.

One common side effect of ibuprofen is gastrointestinal upset. This can include symptoms such as nausea, indigestion, and stomach pain. When combined with alcohol, which is also known to irritate the digestive system, these effects can be even more pronounced.

So if you’re already experiencing stomach issues from taking Advil, adding alcohol into the mix may only exacerbate these problems.

It’s also worth noting that ibuprofen can cause dizziness and drowsiness in some individuals. This can affect your ability to drive or operate machinery safely. Alcohol is a central nervous system depressant that has similar sedating effects on the body.

Combining these substances could increase feelings of sleepiness and impaired coordination.

How Long After Taking Ibuprofen Can You Drink Alcohol?

Can You Drink On Advil (2)

After taking ibuprofen, it is generally advisable to wait at least 24 hours before consuming alcohol. This waiting period allows your body enough time to process the medication and reduces the risk of potential interactions between ibuprofen and alcohol.

Mixing these substances too closely together can lead to stomach irritation, as both ibuprofen and alcohol are known to increase acid production in the stomach.

Additionally, combining them can also increase the risk of gastrointestinal bleedingkidney damagedecreased alertness, and other side effects associated with ibuprofen use.

To ensure your safety and minimize any potential risks, it is always best to consult a healthcare professional for specific advice regarding the safe consumption of both ibuprofen and alcohol.

Safe Usage of Ibuprofen and Alcohol

Can You Drink On Advil (3)

To safely use ibuprofen and alcohol together, it is important to take ibuprofen on occasion and in the recommended dosage, while also practicing moderation when consuming alcohol.

Taking ibuprofen on occasion

Taking ibuprofen on occasion can be safe, as long as it is done responsibly. It is important to follow the recommended dosage and usage instructions provided by your healthcare professional or indicated on the packaging.

Using ibuprofen occasionally, such as for temporary pain relief or to reduce inflammation, can help manage discomfort effectively. However, it is crucial to be mindful of combining ibuprofen with alcohol, as excessive consumption may increase the risk of adverse effects.

It is always best to consult a healthcare professional for personalized advice and guidance regarding the safe use of both ibuprofen and alcohol.


In conclusion, while it is generally safe to have a drink or two while taking Advil, it is important to do so in moderation. Mixing ibuprofen and alcohol can lead to potential risks such as gastrointestinal bleeding and kidney damage.

To ensure your safety, always follow the recommended dosage of Advil and consult with a healthcare professional if you have any concerns.