Updated at: 08-06-2023 - By: John Lau

The question, “Will I die if I drink on Accutane?” is one that may cause a great deal of anxiety for individuals considering taking this powerful prescription acne medication.

It’s crucial to understand the effects of Accutane on your body and its potential interactions with alcohol to ensure your safety throughout the treatment process.

This blog will explore how Accutane works, the risks associated with combining it with alcohol, and steps you can take to minimize these dangers while also effectively treating your acne.

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Understanding Accutane: Effects On The Body And Alcohol Interactions

Accutane is a powerful medication used to treat severe acne, and it works by reducing the production of oil in the skin.

How Accutane Works To Treat Acne

Accutane, also known as isotretinoin, is a potent acne treatment medication derived from Vitamin A. It has gained widespread recognition for its effectiveness in combating severe and persistent acne that may not respond to other treatments.

By targeting the sebaceous glands responsible for oil production, Accutane effectively minimizes the chance of clogged pores and subsequent acne formation. In many cases, individuals on this medication experience dramatic improvements in their skin condition within just a few months of starting treatment.

Potential Side Effects Of Accutane

As a highly effective acne treatment, Accutane is widely used, but it is also associated with various potential side effects that can impact skin health, mental well-being, and liver functioning. People struggling with alcoholism should be aware of these possible issues while using Accutane:

  1. Chapped lips – one of the most common symptoms experienced while on Accutane.
  2. Dry skin – another frequent issue that may require moisturizers to alleviate discomfort.
  3. Itching and dry nasal passages – which can lead to mild nosebleeds.
  4. Mental health issues – a significant concern as Accutane has been linked to depression, mood swings, and even suicidal thoughts in some cases.
  5. Liver toxicity – Accutane can affect liver functioning, increasing the risk of damage when combined with alcohol.
  6. Birth defects – pregnant women or those considering pregnancy should not use Accutane due to the high risk of severe birth abnormalities.
  7. Nausea and abdominal pain – gastrointestinal problems may arise from taking Accutane.
  8. Redness and peeling skin – though temporary, this reaction may cause uncomfortable sensations.

By understanding these potential side effects and discussing any concerns with their healthcare provider, individuals facing alcoholism can make informed decisions about their acne treatment plan while prioritizing overall well-being.

Why Drinking Alcohol While Taking Accutane Is A Concern

Drinking alcohol while taking Accutane can pose significant health risks due to the medication’s interactions with alcohol. These concerns primarily stem from the fact that both substances have a profound effect on liver function.

The active ingredient in Accutane, isotretinoin, already puts stress on the liver as it works to treat severe acne by reducing oil production and inflammation.

Moreover, consuming alcohol increases your chances of experiencing other adverse side effects while undergoing Accutane treatment. Alcohol is known for its depressant effect on the central nervous system (CNS), which can exacerbate mood disorders like depression and anxiety – conditions commonly linked to Accutane use.

Additionally, mixing alcohol and Accutane also heightens other risks such as impaired judgment and decision-making abilities; dehydration resulting from increased urination caused by both substances; and an overall increase in substance abuse potential among those predisposed towards addiction issues.

Risks Of Drinking On Accutane

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Drinking while on Accutane increases the risk of liver damage, depression, seizures, impaired judgment and decision-making, and dehydration.

Increased Liver Damage Risk

Drinking alcohol while taking Accutane can increase the risk of liver damage. Accutane alone, in some instances, can cause harm to the liver, which can become even more dangerous when combined with alcohol.

Alcohol is metabolized by the liver and its excessive consumption will put a strain on this organ leading to liver damage. Combining Accutane with alcohol can worsen liver damage that might result from using Accutane alone as the medication itself also affects how the liver functions.

Moderation is key when drinking alcohol especially if you are already at higher risk because you’re on Accutane treatment. It is advisable to avoid consuming any alcoholic drinks while undergoing this treatment and follow your doctor’s instructions carefully for preserving your overall health.

Heightened Risk Of Depression

Drinking alcohol while taking Accutane can increase the risk of depression, which is a serious mental health problem. Although some studies have found no evidence that isotretinoin, the active ingredient in Accutane, is linked to an increased risk for depression or suicide, it has been reported as a potential side effect.

It’s important to remember that everyone’s reaction to medication and alcohol is different, so there is a possibility that drinking while on Accutane could increase your risk of experiencing depressive symptoms.

Higher Likelihood Of Seizures

Drinking alcohol while taking Accutane for acne treatment increases the likelihood of seizures, potentially leading to serious health issues.

Seizures are caused by abnormal electrical activity in the brain, and alcohol may trigger this incident when taken with Accutane.

It is essential to prioritize your health and safety while on Accutane therapy, avoiding any activities that could put you at higher risks such as drinking alcohol. Apart from being dangerous for people with pre-existing seizures disorder or epilepsy, excessive consumption of alcohol can also damage the liver which is already under stress during the medication period.

Impaired Judgment And Decision-making

Mixing alcohol and Accutane can significantly impair judgment and decision-making abilities. This is because the combination of alcohol and Accutane can cause dizziness, confusion, and disorientation which affects cognitive function.

Additionally, drinking on Accutane increases the risk of seizures which can further worsen cognitive function impairment.

In conclusion, it’s best to avoid consuming alcohol while taking Accutane to prevent any potential risks associated with compromised judgment and decision-making abilities.


When you drink alcohol, it dehydrates your body by increasing urine production and reducing the amount of water that your kidneys absorb. On top of that, Accutane can cause dryness in the mouth and nose, making dehydration more likely to occur.

This is a dangerous combination because severe dehydration can lead to headaches, dizziness, and even fainting. When you are taking Accutane, it’s crucial to stay well hydrated by drinking plenty of water throughout the day.

It’s also important to note that if you experience any symptoms of dehydration while on Accutane – such as dark urine or feeling thirsty – seek medical attention immediately.

Severe cases may require hospitalization or intravenous fluids to replenish lost fluids quickly.

Staying Safe While Taking Accutane

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Follow your doctor’s advice and medication instructions strictly. Avoid alcohol while taking Accutane to prevent any potential interaction that can cause unwanted side effects or worsen liver damage.

Stay hydrated, take care of your liver health, and engage in non-alcoholic social activities while on the medication.

Follow Your Doctor’s Advice And Medication Instructions

It is crucial to follow your doctor’s advice and medication instructions when taking Accutane. Here are some important points to keep in mind:

  • Accutane is a prescription drug and should only be taken under medical supervision.
  • Take Accutane exactly as prescribed by your doctor, at the same time each day.
  • Do not increase or decrease the dosage without your doctor’s approval.
  • If you miss a dose, take it as soon as possible. If it is close to the time for your next dose, skip the missed dose and continue with your regular schedule.
  • Do not share Accutane with others, even if they have similar symptoms or conditions.
  • While taking Accutane, avoid other medications that may interact with it without consulting with your doctor first.

By following these guidelines and working closely with your doctor, you can help ensure that you get the most out of your acne treatment while avoiding any potential risks or complications.

Avoid Alcohol While Taking Accutane

Alcoholism is a serious condition, and drinking while taking Accutane can exacerbate the potential negative side effects of the medication. Accutane is metabolized by the liver, which means that adding alcohol to the mix puts extra stress on this vital organ.

This stress could lead to increased liver damage riskdehydration, and even seizures. It’s important to prioritize your health and avoid alcohol consumption while undergoing treatment with Accutane.

Instead of drinking, consider engaging in non-alcoholic social activities or choosing healthy beverage options to support your well-being during this time.

Stay Hydrated And Take Care Of Your Liver Health

Staying hydrated and taking care of your liver health is crucial while taking Accutane to avoid liver damage. Here are some tips:

  • Drink plenty of water throughout the day to stay hydrated.
  • Avoid sugary drinks and sodas that can dehydrate you.
  • Eat a healthy diet with lots of fruits, vegetables, and whole grains to support liver function.
  • Limit your alcohol consumption or avoid it altogether while taking Accutane to reduce the risk of liver injury.
  • Take breaks from drinking alcohol regularly to give your liver a chance to recover and heal.
  • Keep up with regular liver function tests as directed by your doctor to monitor for any signs of liver damage or injury.

Engage In Non-alcoholic Social Activities

If you are taking Accutane and struggling with alcoholism, it’s important to find ways to socialize without putting yourself at risk. Here are some ideas for non-alcoholic activities:

  • Host a game night with friends and family. Board games, card games, or video games can provide hours of entertainment without the need for alcohol.
  • Take up a new hobby that interests you. Anything from painting to cooking to hiking can be a fun way to meet new people and enjoy yourself.
  • Attend events that don’t involve alcohol. Concerts, theater performances, and art shows are just a few examples of events where you can have a great time without drinking.
  • Join a support group for addiction recovery. These groups offer a safe space to connect with others who understand what you’re going through.
  • Get involved in volunteer work. Helping others can be incredibly fulfilling and is a great way to meet like-minded individuals.

Remember that staying sober while on Accutane is essential for your health and well-being. By seeking out non-alcoholic activities, you can still have fun and live your life while keeping yourself safe.

Choose Healthy Beverages

It is important to make sure you are staying safe while taking Accutane, and choosing healthy beverages can help with that. Here are some tips for choosing healthy beverages:

  • Stick to water as much as possible. Drinking water is essential for staying hydrated and can aid in the absorption of Accutane.
  • Avoid sugary drinks like soda or energy drinks. These can cause dehydration and possibly interfere with the medication’s effectiveness.
  • Try herbal teas or diluted fruit juices for a flavorful alternative to plain water.
  • If you do choose to drink alcohol, make sure to limit your consumption and stay within safe guidelines.
  • Remember that staying hydrated is crucial while taking Accutane, so aim to drink at least 8 glasses of liquid per day.

By choosing healthy beverages, you can support your body while taking Accutane and avoid potential side effects.


In conclusion, mixing alcohol and Accutane is a dangerous combination that can have severe consequences on your health. It’s not worth risking your life or well-being for a night of drinking.

Accutane has already been proven to cause liver damage and putting additional stress on the liver by consuming alcohol can worsen this issue.

Always follow your doctor’s instructions carefully when taking any prescription medication, including Accutane, to ensure you get the best results possible and avoid negative interactions with other substances like alcohol